Smad4 Antibody
Source: Rabbit mAb Catalog No. : CY5014
Smad4 Antibody (CY5014)
UniProt:Q13485
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5014
数据表
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UniProt
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Mol Weight65kDa
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Alternative NamesMAD homolog 4; MAD, mothers against decapentaplegic homolog 4; MADH4; Mothers against decapentaplegic homolog 4; DPC4; hSMAD4; JIP;
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ImmunogenA synthesized peptide derived from human Smad4
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionSmad4 transcription factor that mediates signal transduction by the transforming growth factor superfamily. The common smad (co-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. Promotes binding of the Smad2/Smad4/Fast-1 complex to DNA and provides an activation function required for Smad1 or Smad2 to stimulate transcription.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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Western blot analysis of SMAD4 expression in (1) SH-SY5Y cell lysate; (2) NIH/3T3 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast cancer, using Smad4 Antibody. -
Eplerenone Prevents Atrial Fibrosis via the TGF-β Signaling Pathway. -cardiology -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（1条）
Eplerenone Prevents Atrial Fibrosis via the TGF-β Signaling Pathway.-cardiology
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