CD11b Antibody
Source: Rabbit mAb Catalog No. : CY5019
CD11b Antibody (CY5019)
UniProt:P11215
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（3）
http://www.abways.cn/showproduct.asp?cid=CY5019
数据表
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UniProt
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Mol Weight170kDa
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Alternative NamesCR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6;ITGAM
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ImmunogenA synthesized peptide derived from human CD11b
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of CD11b expression in RAW264.7 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human spleen, using CD11b Antibody. -
Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells. -Journal of Affective Disorders -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
引用文献（3条）
Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells.-Journal of Affective Disorders
Critical Role of TLR4 on the Microglia Activation Induced by Maternal LPS Exposure Leading to ASD-Like Behavior of Offspring-Frontiers in Cell and Developmental Biology (Front. Cell Dev. Biol)
Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement-research square
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