Caveolin-1 Antibody
Source: Rabbit mAb Catalog No. : CY5021
Caveolin-1 Antibody (CY5021)
UniProt:Q03135
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5021
数据表
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UniProt
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Mol Weight20kDa
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Alternative NamesBSCL3; CGL3; caveolin 1, caveolae protein, 22kDa; Caveolin-1; VIP21; CAV; CAV1.
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ImmunogenA synthesized peptide derived from human Caveolin-1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCaveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:20
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All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
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Western blot analysis of Caveolin-1 expression in A431 cell lysate.
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Immunohistochemical analysis of paraffin-embedded mouse lung, using Caveolin-1 Antibody.
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Immunofluorescent analysis of A431 cells, using Caveolin-1 Antibody .
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All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
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Immunofluorescent analysis using the Antibody at 1:50 dilution.