Cleaved PARP Antibody
Source: Rabbit mAb Catalog No. : CY5035
Cleaved PARP Antibody (CY5035)
UniProt:P09874
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（7）
http://www.abways.cn/showproduct.asp?cid=CY5035
数据表
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UniProt
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Mol Weight25kDa
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Alternative NamesPPOL; ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1;
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ImmunogenA synthesized peptide derived from human Cleaved PARP
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionInvolved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:100
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All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of Cleaved PARP expression in (1) RAW264.7 cell lysate;(2) NIH/3T3 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human kidney, using Cleaved PARP Antibody. -
MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression. -Oncogene -
Artemether suppresses cell proliferation and induces apoptosis in diffuse large B cell lymphoma cells. -EXPERIMENTAL AND THERAPEUTIC MEDICINE- EXP THER MED
引用文献（7条）
Artemether suppresses cell proliferation and induces apoptosis in diffuse large B cell lymphoma cells.-EXPERIMENTAL AND THERAPEUTIC MEDICINE- EXP THER MED
MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression.-Oncogene
Cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein K facilitates bovine ephemeral fever virus replication-Veterinary Microbiology
Role of betulinic acid derivative SH‑479 in triple negative breast cancer and bone microenvironment-Oncology Letters (ONCOL LETT)
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells-Aging-US
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