Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) Antibody
Source: Rabbit mAb Catalog No. : CY5044
Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) Antibody (CY5044)
UniProt:P27361
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5044
数据表
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UniProt
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Mol Weight42kDa/44kDa
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Alternative NamesMAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1;
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ImmunogenA synthesized peptide derived from human Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 FC 1:40
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Western blot analysis of Phospho- Erk1 (T202/Y204) + Erk2 (T185/Y187) expression in A431 cell lysate treated with EGF. -
Immunofluorescent analysis using the Antibody at 1:50 dilution.
引用文献（1条）
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
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