p53 Antibody
Source: Rabbit mAb Catalog No. : CY5047
p53 Antibody (CY5047)
UniProt:P04637
Application:WB,ICC/IF,IP,FC
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5047
数据表
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UniProt
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Mol Weight53kDa
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Alternative NamesAntigen NY-CO-13; TP53; Tumor suppressor p53; Cellular tumor antigen p53; Phosphoprotein p53;
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ImmunogenA synthesized peptide derived from human p53
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Western blot analysis of p53 in (1) A431 cell lysate; (2) HEK293 cell lysate.
引用文献（1条）
Deficiency in WDFY4 reduces the number of CD8+ T cells via reactive oxygen species-induced apoptosis-Molecular Immunology (MOL IMMUNOL)
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