pro Caspase 3 Antibody
Source: Rabbit mAb Catalog No. : CY5048
pro Caspase 3 Antibody (CY5048)
UniProt:P42574
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5048
数据表
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UniProt
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Mol Weight35kDa
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Alternative NamesCASP3; Caspase-3; APOPAIN; CPP32; CPP32B; SCA-1;
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ImmunogenA synthesized peptide derived from human pro Caspase 3
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCaspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Western blot analysis of pro Caspase 3 in HeLa cell lysate. -
Immunofluorescent analysis of A673 cells, using pro Caspase 3 Antibody. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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