Caspase-9 Antibody_单克隆抗体-上海泊湾生物技术有限公司

Caspase-9 Antibody

Source: Rabbit mAb Catalog No. : CY5049

Caspase-9 Antibody (CY5049)
UniProt:P55211
Application:WB,IHC,ICC/IF,FC,IP
Reactivity:Human
Source:Rabbit mAb
References（4）
http://www.abways.cn/showproduct.asp?cid=CY5049

 Datasheet

数据表

UniProt

P55211
Mol Weight

48kDa
Alternative Names

APAF-3; Caspase9; ICE-LAP6; Apoptotic protease Mch-6; CASP-9; Caspase-9; Caspase-9 precursor; MCH6; RNCASP9;
Immunogen

A synthesized peptide derived from human Caspase-9
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.

Applications

Reactivity

Human
Application

WB,IHC,ICC/IF,FC,IP
Recommended dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Immunofluorescent analysis using the Antibody at 1:150 dilution.
Western blot analysis of Caspase-9 in HeLa cell lysate treated with Camptothecin.
Immunohistochemical analysis of paraffin-embedded human liver cancer, using Caspase-9 Antibody.
Immunofluorescent analysis of 3T3 cells, using Caspase-9 Antibody.
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer. -OncoTargets and Therapy
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

引用文献（4条）

Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer.-OncoTargets and Therapy

The circular RNA circCPE regulates myoblast development by sponging miR-138-Journal of Animal Science and Biotechnology (J ANIM SCI BIOTECHNO)

Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis-BMC Complementary Medicine and Therapies (BMC COMPLEMENT MED)

N-linoleyltyrosine resisted the growth of non-small cell lung cancer cells via the regulation of CB1 and CB2 involvement of PI3K and ERK pathways-Frontiers in Pharmacology