Caspase-3 Antibody
Source: Rabbit mAb Catalog No. : CY5051
Caspase-3 Antibody (CY5051)
UniProt:P42574
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human
Source:Rabbit mAb
References（6）
http://www.abways.cn/showproduct.asp?cid=CY5051
数据表
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UniProt
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Mol Weight32kDa
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Alternative NamesCASP3; Caspase-3; APOPAIN; CPP32; CPP32B; SCA-1; Caspase3;
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ImmunogenA synthesized peptide derived from human Caspase-3
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCaspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of Caspase-3 in HEK293 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human tonsil, using Caspase-3 Antibody. -
Immunofluorescent analysis of Hela cells, using Caspase-3 Antibody . -
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:3K dilution) -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（6条）
Cytidine monophosphate kinase is inhibited by the TGF-β signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer.-Cellular Signalling
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica.-International Journal of Biological Macromolecules
Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer-Biomaterials
Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice-Frontiers in Pharmacology (Front Pharmacol)
Transcription Factor Nrf2 Modulates Lipopolysaccharide-Induced Injury in Bovine Endometrial Epithelial Cells-INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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