Bax Antibody
Source: Rabbit mAb Catalog No. : CY5059
Bax Antibody (CY5059)
UniProt:Q07812
Application:WB,IHC,IP,FC
Reactivity:Human,Mouse,Rat,Hamster
Source:Rabbit mAb
References（22）
http://www.abways.cn/showproduct.asp?cid=CY5059
数据表
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UniProt
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Mol Weight21kDa
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Alternative NamesApoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
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ImmunogenA synthesized peptide derived from human Bax
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionBax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
Applications
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ReactivityHuman,Mouse,Rat,Hamster
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ApplicationWB,IHC,IP,FC
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma, using the Antibody at 1:200 dilution. -
Immunohistochemical analysis of paraffin-embedded Human Hodgkin's lymphoma, using the Antibody at 1:200 dilution. -
Western blot analysis of Bax in (1) HeLa cell lysate;(2) RAW264.7 Whole Cell Lysate. -
Immunohistochemical analysis of paraffin-embedded human adenocarcinoma of colon, using Bax Antibody. -
Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy. -Toxicology Mechanisms and Methods -
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression. -RSC Advances -
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells. -cancer science -
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:6K dilution)
引用文献（22条）
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells.-cancer science
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica.-International Journal of Biological Macromolecules
Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression.-RSC Advances
Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy.-Toxicology Mechanisms and Methods
JLX001 improves myocardial ischemia-reperfusion injury by activating Jak2-Stat3 pathway-Life Sciences (LIFE SCI)
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