RNF20 Antibody
Source: Rabbit mAb Catalog No. : CY5071
RNF20 Antibody (CY5071)
UniProt:Q5VTR2
Application:WB,ICC/IF,IP,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5071
数据表
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UniProt
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Mol Weight114kDa
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Alternative NamesRING finger protein 20; BRE1A;RNF20;
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ImmunogenA synthesized peptide derived from human RNF20
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionComponent of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
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Western blot analysis of RNF20 in (1) MCF7 cell lysate; (2) HeLa cell lysate.
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