p21 Antibody
Source: Rabbit mAb Catalog No. : CY5088
p21 Antibody (CY5088)
UniProt:P38936
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAb
References（5）
http://www.abways.cn/showproduct.asp?cid=CY5088
数据表
-
UniProt
-
Mol Weight21kDa
-
Alternative NamesCAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; P21cip1;
-
ImmunogenA synthesized peptide derived from human p21
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionThe tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.
Applications
-
ReactivityHuman
-
ApplicationWB,IHC,ICC/IF,IP
-
Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
-
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Immunofluorescent analysis using the Antibody at 1:500 dilution. -
Western blot analysis of p21 in (1) MCF-7 cell lysate; (2) LnCaP cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon, using p21 Antibody. -
Immunofluorescent analysis of MCF7 cells, using p21 Antibody . -
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer. -Oncotarget -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（5条）
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer.-Oncotarget
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways-Molecular Therapy - Nucleic Acids (MOL THER-NUCL ACIDS)
MicroRNA-668-3p inhibits myoblast proliferation and differentiation by targeting Appl1-BMC GENOMICS
CLOCK inhibits the proliferation of porcine ovarian granulosa cells by targeting ASB9-Journal of Animal Science and Biotechnology
销售咨询
一键电话