Alpha Synuclein Antibody
Source: Rabbit mAb Catalog No. : CY5129
Alpha Synuclein Antibody (CY5129)
UniProt:P37840
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5129
数据表
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UniProt
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Mol Weight20kDa
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Alternative NamesAlpha-synuclein; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; PARK1; PARK4; PD1; SNCA;
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ImmunogenA synthesized peptide derived from human Alpha Synuclein
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionMay be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of Alpha Synuclein expression in Human fetal brain lysate. -
Immunohistochemical analysis of paraffin-embedded mouse testis, using Alpha Synuclein Antibody. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution. -
Immunofluorescent analysis using the Antibody at 1:500 dilution.
引用文献（1条）
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells-Molecular Neurobiology (MOL NEUROBIOL)
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