p53 Antibody
Source: Rabbit mAb Catalog No. : CY5131
p53 Antibody (CY5131)
UniProt:P04637
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5131
数据表
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UniProt
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Mol Weight53kDa
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Alternative NamesCellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53;
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ImmunogenA synthesized peptide derived from human p53
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPlays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3k dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:3k dilution for 1 hour at room temperature.
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Western blot analysis of p53 expression in T47D cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon cancer, using p53 Antibody. -
Immunofluorescent analysis of Hela cells, using p53 Antibody .
引用文献（1条）
Synthesis and Antineoplastic Activity of a Dimer, Spiroindolinone Pyrrolidinecarboxamide-MOLECULES
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