Nrf2 Antibody
Source: Rabbit mAb Catalog No. : CY5136
Nrf2 Antibody (CY5136)
UniProt:Q16236
Application:WB,IHC,ICC/IF,IP,CHIP
Reactivity:Human,Mouse
Source:Rabbit mAb
References（6）
http://www.abways.cn/showproduct.asp?cid=CY5136
数据表
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UniProt
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Mol Weight90-110kDa
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Alternative NamesNuclear factor erythroid 2-related factor 2; Nuclear factor, erythroid derived 2, like 2; NFE2-related factor 2; NRF2; NF-E2-related factor 2; NFE2L2; NF2L2; HEBP1
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ImmunogenA synthesized peptide derived from human Nrf2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTranscription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF,IP,CHIP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50
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Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of Nrf2 expression in 293T cell treated with arsenite. -
Immunohistochemical analysis of paraffin-embedded human kidney, using Nrf2 Antibody. -
Immunofluorescent analysis of Hela cells, using Nrf2 Antibody.
引用文献（6条）
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells-Molecular Neurobiology (MOL NEUROBIOL)
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway-Journal of Ethnopharmacology (J ETHNOPHARMACOL)
Sesamol ameliorates dextran sulfate sodiuminduced depression-like and anxiety-like behaviors in colitis mice: the potential involvement of the gut–brain axis-Food & Function
CCN6 improves hepatic steatosis, inflammation, and fibrosis in non-alcoholic steatohepatitis-Liver International
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming-MOLECULAR CARCINOGENESIS
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