PMEL17 / GP100 Antibody
Source: Rabbit mAb Catalog No. : CY5149
PMEL17 / GP100 Antibody (CY5149)
UniProt:P40967
Application:WB,IHC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5149
数据表
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UniProt
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Mol Weight100kDa
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Alternative NamesPMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;
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ImmunogenA synthesized peptide derived from human PMEL17 / GP100
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPlays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Applications
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ReactivityHuman
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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Western blot analysis of PMEL17 / GP100 expression in human melanoma lysate. -
Immunohistochemical analysis of paraffin-embedded human melanoma, using PMEL17 / GP100 Antibody.
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