STAT3 Antibody
Source: Rabbit mAb Catalog No. : CY5165
STAT3 Antibody (CY5165)
UniProt:P40763
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（4）
http://www.abways.cn/showproduct.asp?cid=CY5165
数据表
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UniProt
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Mol Weight88kDa
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Alternative NamesAPRF, Acute-phase response factor, Signal transducer and activator of transcription 3
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ImmunogenA synthesized peptide derived from human STAT3
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:200~1:500
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of STAT3 expression in (1) A431 cell lysate; (2) Raji cell lysate. -
Immunohistochemical analysis of paraffin-embedded human thyroid carcinoma, using STAT3 Antibody. -
Immunofluorescent analysis of HeLa cells, using STAT3 Antibody. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution.
引用文献（4条）
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
CXCL3 overexpression affects the malignant behavior of oral squamous cell carcinoma cells via the MAPK signaling pathway-JOURNAL OF ORAL PATHOLOGY & MEDICINE (J ORAL PATHOL MED)
Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma-BIOSCIENCE REPORTS (Biosci Rep)
USP18‑deficiency in cervical carcinoma is crucial for the malignant behavior of tumor cells in an ERK signal‑dependent manner-Oncology Letters (ONCOL LETT)
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