MMP2 Antibody
Source: Rabbit mAb Catalog No. : CY5189
MMP2 Antibody (CY5189)
UniProt:P08253
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（6）
http://www.abways.cn/showproduct.asp?cid=CY5189
数据表
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UniProt
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Mol Weight72kDa
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Alternative Names72 kDa gelatinase; 72 kDa type IV collagenase; CLG4; CLG4A; collagenase type IV-A; Gelatinase A; Matrix metalloproteinase-2; matrix metalloproteinase-II; MMP2; MMPII;
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ImmunogenA synthesized peptide derived from human MMP2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionMMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:200
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of MMP2 expression in (1)L6 cell lysate;(2)HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast adenocarcinoma, using MMP2 Antibody. -
CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. -Molecular Cancer
引用文献（6条）
Cytidine monophosphate kinase is inhibited by the TGF-β signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer.-Cellular Signalling
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica.-International Journal of Biological Macromolecules
CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling.-Molecular Cancer
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice-JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH(J EXP CLIN CANC RES)
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial–Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma-Foods
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