PSMA Antibody
Source: Rabbit mAb Catalog No. : CY5192
PSMA Antibody (CY5192)
UniProt:Q04609
Application:WB,IHC,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5192
数据表
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UniProt
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Mol Weight110kDa
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Alternative NamesFGCP;FOLH 1;GCP 2;GCPII;mGCP;NAALADase I;PSM;PSMA
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ImmunogenA synthesized peptide derived from human PSMA
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPSMA has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Applications
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ReactivityHuman
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ApplicationWB,IHC,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
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Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of PSMA expression in LnCaP cell lysate. -
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using PSMA Antibody. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature.
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