ATM Antibody
Source: Rabbit mAb Catalog No. : CY5207
ATM Antibody (CY5207)
UniProt:Q13315
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5207
数据表
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UniProt
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Mol Weight350kDa
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Alternative NamesA-T, mutated; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; EC 2.7.11.1; kinase ATM; Serine-protein kinase ATM
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ImmunogenA synthesized peptide derived from human ATM
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:200 FC 1:50
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Western blot analysis of ATM expression in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast cancer, using ATM Antibody. -
Immunofluorescent analysis of Hela cells, using ATM Antibody. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.
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