LRP1 Antibody
Source: Rabbit mAb Catalog No. : CY5215
LRP1 Antibody (CY5215)
UniProt:Q07954
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5215
数据表
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UniProt
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Mol Weight85kDa
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Alternative NamesA2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5;
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ImmunogenA synthesized peptide derived from human LRP1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionEndocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:10000~1:20000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30 FC 1:50
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All lanes use the Antibody at 1:3W dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:300 dilution. -
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:300 dilution. -
Immunohistochemical analysis of paraffin-embedded Human breast cancer, using the Antibody at 1:300 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of LRP1 expression in A549 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human liver carcinoma, using LRP1 Antibody. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
引用文献（1条）
LDL receptor related protein 1 is an adverse prognostic biomarker that correlates with stromal remodeling and macrophages infiltration in bladder cancer-Frontiers in Immunology
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