PI 3 kinase p110 alpha Antibody_单克隆抗体-上海泊湾生物技术有限公司

PI 3 kinase p110 alpha Antibody

Source: Rabbit mAb Catalog No. : CY5224

PI 3 kinase p110 alpha Antibody (CY5224)
UniProt:P42336
Application:WB,ICC/IF,IP,
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5224

 Datasheet

数据表

UniProt

P42336
Mol Weight

110kDa
Alternative Names

PI 3 Kinase catalytic subunit alpha; phosphoinositide-3-kinase catalytic alpha polypeptide; PI3-kinase p110 alpha; PI3K; PI3K p110-alpha; PK3CA; PIK3CA; PtdIns-3-kinase p110
Immunogen

A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Applications

Reactivity

Human,Mouse,Rat
Application

WB,ICC/IF,IP,
Recommended dilution

WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:20

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Western blot analysis of PI 3 kinase p110 alpha expression in Jurkat cell lysate.Western blot analysis of PI 3 kinase p110 alpha expression in Jurkat cell lysate.
Immunofluorescent analysis using the Antibody at 1:25 dilution.
Immunofluorescent analysis using the Antibody at 1:100 dilution.