Raf1 Antibody
Source: Rabbit mAb Catalog No. : CY5225
Raf1 Antibody (CY5225)
UniProt:P04049
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5225
数据表
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UniProt
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Mol Weight74kDa
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Alternative NamesC-RAF, C-Raf, CRAF, EC 2.7.11.1, Protein kinase raf 1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, Raf-1, kinase Raf1
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ImmunogenA synthesized peptide derived from human Raf1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRaf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of Raf1 expression in K562 cell lysate. -
Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin. -Clinical Epigenetics -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（1条）
Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin.-Clinical Epigenetics
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