PTEN Antibody
Source: Rabbit mAb Catalog No. : CY5231
PTEN Antibody (CY5231)
UniProt:P60484
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References(2)
http://www.abways.cn/showproduct.asp?cid=CY5231
数据表
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UniProt
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Mol Weight54kDa
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Alternative NamesBZS; DEC; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del;
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ImmunogenA synthesized peptide derived from human PTEN
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.
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Western blot analysis of extracts of MCF-7 cell lysate, using PTEN antibody.
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Immunohistochemical analysis of paraffin-embedded human kidney, using PTEN Antibody .
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Immunofluorescent analysis of HeLa cells, using PTEN Antibody .
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Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes. -Biochemical and Biophysical Research Communications(BIOCHEM BIOPH RES CO)
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Immunofluorescent analysis using the Antibody at 1:50 dilution.
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Immunofluorescent analysis using the Antibody at 1:150 dilution.
引用文献(2条)
Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes.-Biochemical and Biophysical Research Communications(BIOCHEM BIOPH RES CO)
An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells-Cell Death & Disease (CELL DEATH DIS)



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