Phospho-EGFR (Y1092) Antibody
Source: Rabbit mAb Catalog No. : CY5232
Phospho-EGFR (Y1092) Antibody (CY5232)
UniProt:P00533
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5232
数据表
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UniProt
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Mol Weight170kDa
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Alternative NamesERBB1, Epidermal growth factor receptor precursor;Receptor protein-tyrosine kinase ErbB-1; kinase EGFR; HER1; EGFR; SA7; NISBD2;
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ImmunogenA synthesized peptide derived from human EGFR Full-length sequence 1210aa around the phosphorylation site of Tyrosine 1092
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionReceptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. Can be phosphorylated and activated by Src.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of EGFR phosphorylation expression in A431 cell treated with EGF. -
Immunohistochemical analysis of paraffin-embedded human breast cancer, using Phospho-EGFR (Y1092) Antibody . -
Immunofluorescent analysis using the Antibody at 1:25 dilution. -
Immunofluorescent analysis using the Antibody at 1:25 dilution.
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