LDL Receptor Antibody
Source: Rabbit mAb Catalog No. : CY5235
LDL Receptor Antibody (CY5235)
UniProt:P01130
Application:WB,IHC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5235
数据表
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UniProt
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Mol Weight95kDa
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Alternative NamesFH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;
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ImmunogenA synthesized peptide derived from human LDL Receptor
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionBinds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC
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Recommended dilutionWB 1:1000~1:2000 IHC 1:100~1:500
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Western blot analysis of LDLR expression in HepG2 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human liver carcinoma, using LDL Receptor Antibody .
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