p57 Kip2 Antibody
Source: Rabbit mAb Catalog No. : CY5249
p57 Kip2 Antibody (CY5249)
UniProt:P49918
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5249
数据表
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UniProt
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Mol Weight57kDa
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Alternative NamesBWCR; BWS; KIP2; WBS; p57; p57 Kip2; WBS ; CDKN1C; Cyclin dependent kinase inhibitor 1C
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ImmunogenA synthesized peptide derived from human p57 Kip2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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Descriptionp27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:50 dilution. -
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer, using the Antibody at 1:50 dilution. -
Immunohistochemical analysis of paraffin-embedded Human tongue cancer, using the Antibody at 1:50 dilution. -
Western blot analysis on HeLa cell using p57 Kip2 Antibody. -
Immunohistochemical analysis of paraffin-embedded rat kidney, using p57 Kip2 Antibody . -
Immunofluorescent analysis of HeLa cells treated with dexamethasone, using p57 Kip2 Antibody . -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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