CDC7 Antibody
Source: Rabbit mAb Catalog No. : CY5252
CDC7 Antibody (CY5252)
UniProt:O00311
Application:WB,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5252
数据表
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UniProt
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Mol Weight70kDa
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Alternative NamesCell division cycle 7-related protein kinase, EC 2.7.11.1, CDC7-related kinase, HsCdc7, huCdc7, CDC7, CDC7L1; Hsk1 ; CDC7 kinase
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ImmunogenA synthesized peptide derived from human CDC7
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionDNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins).
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,FC
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Recommended dilutionWB 1:1000~1:2000 FC 1:100
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Western blot analysis of extracts from HeLa cells, using CDC7 antibody.
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