NOX4 Antibody
Source: Rabbit mAb Catalog No. : CY5255
NOX4 Antibody (CY5255)
UniProt:Q9NPH5
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（4）
http://www.abways.cn/showproduct.asp?cid=CY5255
数据表
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UniProt
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Mol Weight67kDa
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Alternative NamesNADPH oxidase 4; Kidney oxidase-1; KOX-1; KOX1; Kidney superoxide-producing NADPH oxidase; Renal NAD(P)H-oxidase; NOX4; RENOX;
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ImmunogenA synthesized peptide derived from human NOX4
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Western blot analysis of NOX4 expression in JAR cell lysate. -
Immunohistochemical analysis of paraffin-embedded rat kidney, using NOX4 Antibody . -
Immunofluorescent analysis of HeLa cells, using NOX4 Antibody . -
Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic rats. -Scientific Reports -
Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic rats. -Scientific Reports -
Immunofluorescent analysis using the Antibody at 1:50 dilution.
引用文献（4条）
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats.-Free Radical Biology and Medicine
Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic rats.-Scientific Reports
Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic rats-Free Radical Biology and Medicine
Inhibition of vascular adventitial remodeling by netrin-1 in diabetic rats-J Biol Chem (JOURNAL OF BIOLOGICAL CHEMISTRY)
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