Q00613

82kDa

HSF1; HSTF 1; HSTF1; Heat shock factor protein 1; Heat shock transcription factor 1;

A synthesized peptide derived from human Phospho-HSF1 (S326)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.

Human

WB,IHC,ICC/IF,IP,FC

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50