SOX2 Antibody
Source: Rabbit mAb Catalog No. : CY5268
SOX2 Antibody (CY5268)
UniProt:P48431
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse
Source:Rabbit mAb
References（3）
http://www.abways.cn/showproduct.asp?cid=CY5268
数据表
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UniProt
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Mol Weight34kDa
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Alternative NamesSOX2; ANOP3; MCOPS3; MGC2413; lcc; SRY related HMG box 2;
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ImmunogenA synthesized peptide derived from human SOX2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTranscription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:500 dilution. -
Western blot analysis of SOX2 expression in (1) NCCIT cell lysate; (2) F9 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human cervix carcinoma, using SOX2 Antibody. -
Immunofluorescent analysis of NCCIT cells, using SOX2 Antibody .
引用文献（3条）
BTF3 promotes stemness and inhibits TypeIInterferon signaling pathway in triple-negative breast cancer-Biochemical and Biophysical Research Communications (BIOCHEM BIOPH RES CO)
REC8 enhances stemness and promotes metastasis of colorectal cancer through BTK/Akt/β-catenin signaling pathway-Translational Oncology (TRANSL ONCOL）
IL-8/CXCR2 mediates tropism of human bone marrow-derived mesenchymal stem cells toward CD133+/CD44+ Colon cancer stem cells-Journal of Cellular Physiology (J Cell Physiol)
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