ErbB3 (HER3) Antibody
Source: Rabbit mAb Catalog No. : CY5270
ErbB3 (HER3) Antibody (CY5270)
UniProt:P21860
Application:WB,IP
Reactivity:Human,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5270
数据表
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UniProt
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Mol Weight185kDa
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Alternative NamesERB3, ERBB3, HER3, c-erbB3, kinase ErbB3
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ImmunogenA synthesized peptide derived from human ErbB3 (HER3)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThis membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.
Applications
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ReactivityHuman,Rat
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ApplicationWB,IP
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Recommended dilutionWB 1:500~1:2000 IP 1:30
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Western blot analysis of ErbB3 (HER3) expression in MCF-7 cell lysate. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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