Phospho-PKR (T446) Antibody
Source: Rabbit mAb Catalog No. : CY5271
Phospho-PKR (T446) Antibody (CY5271)
UniProt:P19525
Application:WB,IHC,IP,ChIP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5271
数据表
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UniProt
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Mol Weight68kDa
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Alternative NamesE2AK2;E2AK2; EIF2AK1; EIF2AK2; MGC126524; PKR p68 kinase; PKR; PRKR;
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ImmunogenA synthesized peptide derived from human Phospho-PKR (T446)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
Applications
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ReactivityHuman
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ApplicationWB,IHC,IP,ChIP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of PKR phosphorylation expression in HeLa cell lysate treated with Calyculin A and TNF-alpha. -
Immunohistochemical analysis of paraffin-embedded human colon, using Phospho-PKR (T446) Antibody.
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