Paxillin Antibody
Source: Rabbit mAb Catalog No. : CY5274
Paxillin Antibody (CY5274)
UniProt:P49023
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5274
数据表
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UniProt
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Mol Weight60kDa
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Alternative NamesPaired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha;
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ImmunogenA synthesized peptide derived from human Paxillin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:50
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Western blot analysis of Paxillin expression in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Paxillin Antibody.
引用文献（1条）
Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis-Theranostics
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