Thrombomodulin Antibody
Source: Rabbit mAb Catalog No. : CY5279
Thrombomodulin Antibody (CY5279)
UniProt:P07204
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5279
数据表
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UniProt
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Mol Weight60kDa
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Alternative NamesCD141; Fetomodulin; THBD; THRM; thrombomodulin; TM;
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ImmunogenA synthesized peptide derived from human Thrombomodulin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Western blot analysis of Thrombomodulin expression in human placenta lysate. -
Immunohistochemical analysis of paraffin-embedded human bladder, using Thrombomodulin Antibody.
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