JAK2 Antibody
Source: Rabbit mAb Catalog No. : CY5287
JAK2 Antibody (CY5287)
UniProt:O60674
Application:WB,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5287
数据表
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UniProt
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Mol Weight130kDa
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Alternative NamesEC 2.7.10.2; JAK-2; JAK2; Janus kinase 2; kinase Jak2; JTK10; THCYT3;
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ImmunogenA synthesized peptide derived from human JAK2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPhosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50-100
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of JAK2 expression in Jurkat cell lysate. -
Immunofluorescent analysis of Jurkat cells, using JAK2 Antibody . -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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