STAT3 Antibody
Source: Rabbit mAb Catalog No. : CY5292
STAT3 Antibody (CY5292)
UniProt:P40763
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5292
数据表
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UniProt
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Mol Weight88kDa
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Alternative NamesAPRF;Acute-phase response factor;Signal transducer and activator of transcription 3; STAT3; HIES;
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ImmunogenA synthesized peptide derived from human STAT3
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTranscription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human Hodgkin's lymphoma, using the Antibody at 1:50 dilution. -
Immunohistochemical analysis of paraffin-embedded Human astrocytoma, using the Antibody at 1:50 dilution. -
Western blot analysis of STAT3 expression in (1) A431 cell lysate; (2) Human liver lysate; (3) Mouse heart lysate; (4) Rat brain lysate. -
Immunohistochemical analysis of paraffin-embedded rat brain, using STAT3 Antibody. -
Immunofluorescent analysis of Hela cells treated with IFNalpha, using STAT3 Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（1条）
Anisotropic active ligandations in siRNA-Loaded hybrid nanodiscs lead to distinct carcinostatic outcomes by regulating nano-bio interactions-Biomaterials
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