O60216

72,128kDa

hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog; HR21;KIAA0078; NXP1;Rad21;

A synthesized peptide derived from human Rad21

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

Human,Mouse,Rat

WB,FC

WB 1:500~1:1000 FC 1:50