CD45 Antibody
Source: Rabbit mAb Catalog No. : CY5311
CD45 Antibody (CY5311)
UniProt:P08575
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5311
数据表
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UniProt
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Mol Weight150kDa
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Alternative NamesCD45; B220; GP180; LCA; PTPRC; T200 leukocyte common antigen;
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ImmunogenA synthesized peptide derived from human CD45
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionProtein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:100 FC 1:20
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Immunohistochemical analysis of paraffin-embedded Rat stomach, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human placenta, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Mouse lung, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Mouse skin, using the Antibody at 1:100 dilution. -
Western blot analysis of CD45 expression in Jurkat cell lysate. -
Immunohistochemical analysis of paraffin-embedded human spleen, using CD45 Antibody .
引用文献（1条）
LDL receptor related protein 1 is an adverse prognostic biomarker that correlates with stromal remodeling and macrophages infiltration in bladder cancer-Frontiers in Immunology
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