P49407

50kDa

ARRB1; ARB1; ARR1; Arrestin beta 1; Beta arrestin 1;

A synthesized peptide derived from human ARRB1

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

Arrestin proteins function as negative regulators of G protein-coupled receptor (GPCR) signaling. Cognate ligand binding stimulates GPCR phosphorylation, which is followed by binding of arrestin to the phosphorylated GPCR and the eventual internalization of the receptor and desensitization of GPCR signaling. Four distinct mammalian arrestin proteins are known. Arrestin 1 (also known as S-arrestin) and arrestin 4 (X-arrestin) are localized to retinal rods and cones, respectively.

Human,Mouse,Rat

WB,IHC,ICC/IF,FC

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:20