5T4 Antibody
Source: Rabbit mAb Catalog No. : CY5323
5T4 Antibody (CY5323)
UniProt:Q13641
Application:WB,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5323
数据表
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UniProt
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Mol Weight72kDa
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Alternative Names5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen;Trophoblast glycoprotein;
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ImmunogenA synthesized peptide derived from human 5T4
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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Description5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IP
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Recommended dilutionWB 1:500~1:2000 IP 1:50
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Western blot analysis of 5T4 expression in MCF-7 cell lysate.
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