PI 3 Kinase p85 alpha Antibody
Source: Rabbit mAb Catalog No. : CY5355
PI 3 Kinase p85 alpha Antibody (CY5355)
UniProt:P27986
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（9）
http://www.abways.cn/showproduct.asp?cid=CY5355
数据表
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UniProt
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Mol Weight85kDa
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Alternative NamesGRB1; P85A; PI3-kinase p85-alpha; PI3K; PI3K p85-alpha; ptdIns-3-kinase p85-alpha;
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ImmunogenA synthesized peptide derived from human PI 3 Kinase p85 alpha
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature. -
Western blot analysis of PI 3 Kinase p85 alpha expression in A431 cell lysate.
引用文献（9条）
LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway.-Journal of Experimental & Clinical Cancer Research
Electro-acupuncture attenuates the mice premature ovarian failure via mediating PI3K/AKT/mTOR pathway.-Life Sciences
Kuntai capsule attenuates premature ovarian failure through the PI3K/AKT/mTOR pathway.-Journal of Ethnopharmacology
Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway-Journal of Ethnopharmacology (J ETHNOPHARMACOL)
Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference-Cellular and Molecular Neurobiology (CELL MOL NEUROBIOL)
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