CXCR4 Antibody_单克隆抗体-上海泊湾生物技术有限公司

CXCR4 Antibody

Source: Rabbit mAb Catalog No. : CY5380

CXCR4 Antibody (CY5380)
UniProt:P61073
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5380

 Datasheet

数据表

UniProt

P61073
Mol Weight

43kDa
Alternative Names

CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;
Immunogen

A synthesized peptide derived from human CXCR4
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

Applications

Reactivity

Human,Mouse
Application

WB,IHC,ICC/IF
Recommended dilution

WB 1:100~1:200 IHC 1:50~1:200 ICC/IF 1:50~1:200

All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
Western blot analysis of CXCR4 expression in Jurkat cell lysate.
Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, using CXCR4 Antibody.
Immunofluorescent analysis of Jurkat cells, using CXCR4 Antibody .
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
Immunofluorescent analysis using the Antibody at 1:50 dilution.