Cyclin D1 Antibody
Source: Rabbit mAb Catalog No. : CY5404
Cyclin D1 Antibody (CY5404)
UniProt:P24385
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（14）
http://www.abways.cn/showproduct.asp?cid=CY5404
数据表
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UniProt
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Mol Weight34kDa
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Alternative NamesCCND1;BCL1; D11S287E; PRAD1; U21B31; Cyclin D1;
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ImmunogenA synthesized peptide derived from human Cyclin D1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPhosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:100 IP 1:50
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All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5W dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human squamous cell carcinoma , using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer, using the Antibody at 1:500 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of Cyclin D1 expression in (1)MCF-7 cell lysates;(2) LnCaP cell lysates. -
Immunohistochemical analysis of paraffin-embedded human bladder, using Cyclin D1 Antibody. -
Immunofluorescent analysis of MCF-7 cells, using Cyclin D1 Antibody . -
miR‐139‐5p reverses stemness maintenance and metastasis of colon cancer stem‐like cells by targeting E2‐2. -JOURNAL OF CELLULAR PHYSIOLOGY -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:6K dilution)
引用文献（14条）
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.-ONCOLOGY LETTERS
miR‐139‐5p reverses stemness maintenance and metastasis of colon cancer stem‐like cells by targeting E2‐2.-JOURNAL OF CELLULAR PHYSIOLOGY
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice-JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH(J EXP CLIN CANC RES)
Hsa_circ_0001982 promotes the progression of breast cancer through miR-1287-5p/MUC19 axis under hypoxia-World Journal of Surgical Oncology (WORLD J SURG ONCOL)
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis-Molecular Cancer (MOL CANCER)
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