PBR Antibody
Source: Rabbit mAb Catalog No. : CY5408
PBR Antibody (CY5408)
UniProt:P30536
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5408
数据表
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UniProt
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Mol Weight18kDa
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Alternative NamesTSPO; PBR; BZRP; IBP; MBR; PKBS; Mitochondrial benzodiazepine receptor; Peripheral benzodiazepine receptor;
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ImmunogenA synthesized peptide derived from human PBR
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPeroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation. A cytoplasmic protein, PRAX-1 （peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of Calreticulin expression in (1) U87-MG cell lysate; (2) A431 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon, using PBR Antibody . -
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:3K dilution)
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