Caspase-1 Antibody
Source: Rabbit mAb Catalog No. : CY5429
Caspase-1 Antibody (CY5429)
UniProt:P29466
Application:WB,IHC
Reactivity:Human,Rat
Source:Rabbit mAb
References（2）
http://www.abways.cn/showproduct.asp?cid=CY5429
数据表
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UniProt
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Mol Weight45kDa
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Alternative NamesCASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;
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ImmunogenA synthesized peptide derived from human Caspase-1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Applications
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ReactivityHuman,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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Western blot analysis of Caspase-1 in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human liver, using Caspase-1 Antibody. -
All lanes use the Antibody at 1:5W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5W dilution for 1 hour at room temperature.
引用文献（2条）
Trimethylamine N-Oxide Exacerbates Renal Inflammation and Fibrosis in Rats With Diabetic Kidney Disease-Frontiers in Physiology (FRONT PHYSIOL)
Oxymatrine blocks the NLRP3 inflammasome pathway, partly downregulating the inflammatory responses of M1 macrophages differentiated from THP-1 monocytes-Biochemistry and Biophysics Reports
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