Histone H3 (mono methyl K18) Antibody
Source: Rabbit mAb Catalog No. : CY5484
Histone H3 (mono methyl K18) Antibody (CY5484)
UniProt:P68431
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5484
数据表
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UniProt
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Mol Weight15kDa
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Alternative NamesH3 histone; HIST1H3A; Histone cluster 1, H3a; H3K18me1;
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ImmunogenA synthesized peptide derived from human Histone H3 (mono methyl K18)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionH3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:500~1:2000 ICC/IF 1:100~1:500
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Western blot analysis of Histone H3 (mono methyl K18) expression in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human liver, using Histone H3 (mono methyl K18) Antibody. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.
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