MLKL Antibody
Source: Rabbit mAb Catalog No. : CY5493
MLKL Antibody (CY5493)
UniProt:Q8NB16
Application:WB,IHC
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5493
数据表
-
UniProt
-
Mol Weight54kDa
-
Alternative NamesMixed lineage kinase domain-like protein; hMLKL;
-
ImmunogenA synthesized peptide derived from human MLKL
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionPseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Applications
-
ReactivityHuman
-
ApplicationWB,IHC
-
Recommended dilutionWB 1:500~1:2000 IHC 50~200
-
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Western blot analysis of MLKL expression in HUVEC cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon, using MLKL Antibody. -
Targeting CAND1 promotes caspase-8/RIP1-dependent apoptosis in liver cancer cells. -Am J Transl Res(AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH) -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（1条）
Targeting CAND1 promotes caspase-8/RIP1-dependent apoptosis in liver cancer cells.-Am J Transl Res(AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH)
销售咨询
一键电话