c-Maf Antibody
Source: Rabbit mAb Catalog No. : CY5511
c-Maf Antibody (CY5511)
UniProt:O75444
Application:IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5511
数据表
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UniProt
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Mol WeightkDa
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Alternative NamesAvian musculoaponeurotic fibrosarcoma (MAF) protooncogene; c-MAF; c-maf proto-oncogene; cMaf; MAF; MGC71685; Proto-oncogene c-Maf;
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ImmunogenA synthesized peptide derived from human c-Maf
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionActs as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationIHC
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Recommended dilutionIHC 1:50~1:200
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Immunohistochemical analysis of paraffin-embedded human kidney, using c-Maf Antibody.
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