HIF-1 beta Antibody _单克隆抗体-上海泊湾生物技术有限公司

HIF-1 beta Antibody

Source: Rabbit mAb Catalog No. : CY5538

HIF-1 beta Antibody  (CY5538)
UniProt:P27540
Application:WB,IHC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5538

数据表

UniProt

P27540
Mol Weight

87kDa
Alternative Names

ARNT;HIF-1beta;HIF1B;HIF1BETA;TANGO;bHLHe2;
Immunogen

A synthesized peptide derived from human HIF-1 beta
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.

Applications

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Western blot analysis of HIF-1 beta expression in Human fetal kidney lysate.
Immunohistochemical analysis of paraffin-embedded human colon, using HIF-1 beta Antibody .
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.